Title :
Characterization of Brownian dynamics induced by glucose using time-domain optical coherence tomography
Author :
Li, Jianjun ; Li, Zhifang ; Li, Hui ; Lin, Xiaona
Author_Institution :
Key Lab. of Optoelectron. Sci. & Imaging for Med., Fujian Normal Univ., Fuzhou, China
Abstract :
Our purpose is to characterize the Brownian motion of glucose concentration in Intralipid solution using time-domain optical coherence tomography (OCT) incorporated with wavelet power spectrum. The results show that the standard deviation (SD) of frequency in the superficial layer, linearly proportional to Brownian diffusion coefficient, is independent of the depth. Our preliminary results demonstrate that SD is inversely proportional to the glucose concentration in Intralipid solution, since the Brownian diffusion coefficient is related to concentration. Thus the SD of frequency in OCT signal is capable of distinguishing the glucose concentration.
Keywords :
Brownian motion; biochemistry; biodiffusion; biological techniques; molecular biophysics; optical tomography; organic compounds; Brownian diffusion coefficient; Intralipid solution; glucose concentration Brownian motion; glucose induced Brownian dynamics characterisation; optical coherence tomography; superficial layer; time domain OCT; wavelet power spectrum; Biomedical optical imaging; Optical interferometry; Optical scattering; Optical sensors; Sugar; Wavelet transforms; Brownian diffusion; Optical coherence tomography; turbid media; wavelet;
Conference_Titel :
Biomedical Engineering and Informatics (BMEI), 2011 4th International Conference on
Conference_Location :
Shanghai
Print_ISBN :
978-1-4244-9351-7
DOI :
10.1109/BMEI.2011.6098394
