Title :
Reconfigurable computing solution for Peptide Mass Fingerprinting
Author :
Bogdan, I. ; Beynon, R.J. ; Coca, D.
Author_Institution :
Dept. of Autom. Control & Syst. Eng., Univ. of Sheffield, Sheffield
Abstract :
The paper describes a high-performance rcconfigurable computing solution for real-time peptide mass fingerprinting. The FPGA system can process the raw mass spectrum generated by a MALDI-ToF mass spectrometer and perform a search against the entire MSDB database in 240 ms. This represents an almost 2000 fold speed up compared with an equivalent software implementation in C, running on a single 3 GHz Xeon workstation.
Keywords :
biology computing; biomolecular electronics; field programmable gate arrays; proteins; reconfigurable architectures; time of flight mass spectrometers; FPGA system; MALDI-ToF mass spectrometer; MSDB database; Xeon workstation; equivalent software implementation; high-performance rcconfigurable computing; raw mass spectrum; real-time peptide mass fingerprinting; reconfigurable computing; Data processing; Databases; Field programmable gate arrays; Fingerprint recognition; Hardware; Instruments; Mass spectroscopy; Peptides; Proteins; Proteomics;
Conference_Titel :
Optimization of Electrical and Electronic Equipment, 2008. OPTIM 2008. 11th International Conference on
Conference_Location :
Brasov
Print_ISBN :
978-1-4244-1544-1
Electronic_ISBN :
978-1-4244-1545-8
DOI :
10.1109/OPTIM.2008.4602499
