DocumentCode :
2629475
Title :
Microbubbles for ultrasound diagnosis and therapy
Author :
Fowlkes, J.B. ; Kripfgans, O.D. ; Carson, P.L.
Author_Institution :
Dept. of Radiol., Michigan Univ., Ann Arbor, MI, USA
fYear :
2004
fDate :
15-18 April 2004
Firstpage :
29
Abstract :
Methods for the local production of microbubbles in vivo are being developed for applications in both diagnostic and therapeutic ultrasound. The techniques involve the use of superheated perfluorocarbon droplets that can be vaporized by the application on focused ultrasound. This provides localization of the resulting gas bubbles and control over the number density and size of bubbles being released. For therapeutic ultrasound, large gas bubbles are produced in numbers sufficient to restrict blood flow or the bubbles can act as nuclei for cavitation-based tissue disruption. In lower number density, the bubbles provide targets with ideal properties for aberration correction, which can be used to improve both therapeutic and diagnostic fields.
Keywords :
biological tissues; biomedical ultrasonics; bubbles; cavitation; drops; patient diagnosis; radiation therapy; aberration correction; blood flow restriction; cavitation-based tissue disruption; gas bubbles; microbubbles; superheated perfluorocarbon droplets; therapeutic ultrasound; ultrasound diagnosis; Biomedical acoustics; Biomedical equipment; In vivo; Lipidomics; Medical services; Medical treatment; Optical microscopy; Radiation detectors; Temperature; Ultrasonic imaging;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Biomedical Imaging: Nano to Macro, 2004. IEEE International Symposium on
Print_ISBN :
0-7803-8388-5
Type :
conf
DOI :
10.1109/ISBI.2004.1398466
Filename :
1398466
Link To Document :
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