Title :
Confocal fiber-optic nanobiosensing
Author :
Ilev, Ilko K. ; Waynant, Ronald W.
Author_Institution :
U.S. Food & Drug Adm., Rockville, MD, USA
Abstract :
A novel concept for noninvasive high-resolution confocal biosensing based on simple apertureless fiber-optic confocal designs including either dual-confocal or single-fiber sensor systems is developed. The method can be employed for precise micron/submicron sensing the optical properties of various tissue layers and bulk samples.
Keywords :
biological techniques; biological tissues; fibre optic sensors; optical design techniques; optical microscopy; dual-confocal fiber sensor; micron/submicron sensing; nanobiosensing; single-fiber sensor; tissue layers; Biomedical optical imaging; Biosensors; High-resolution imaging; Optical design; Optical fiber sensors; Optical imaging; Optical microscopy; Optical sensors; Sensor systems; Spatial resolution; Confocal Microscopy; Fiber Optic Biosensors; Noninvasive Optical Sensing;
Conference_Titel :
Lasers and Electro-Optics Society, 2005. LEOS 2005. The 18th Annual Meeting of the IEEE
Print_ISBN :
0-7803-9217-5
DOI :
10.1109/LEOS.2005.1547929
