Title :
In silico design of guiding tracks for molecular shuttles powered by motor proteins
Author_Institution :
Dept. of Math. & Design Eng., Gifu Univ., Gifu, Japan
Abstract :
Living cells utilize motor proteins, which are biological molecular machines, to maintain their functions. For instance, a motor protein carries a cargo along a cytoskeletal filament, delivering the cargo to its destination. Molecular shuttles powered by motor proteins are bio-inspired material transport systems for Lab-on-a-Chip devices. In the molecular shuttle systems, cytoskeletal filaments loading cargos are transported by motor proteins along microfabricated guiding tracks.
Keywords :
biological techniques; biomechanics; cellular biophysics; lab-on-a-chip; microfabrication; molecular biophysics; organic compounds; proteins; tracking; bioinspired material transport systems; biological molecular machines; cytoskeletal filament; cytoskeletal filaments loading cargos; in silico design; lab-on-a-chip devices; living cells; microfabricated guiding tracks; molecular shuttle systems; motor proteins; Educational institutions; Fabrication; Lab-on-a-chip; Materials; Physics; Proteins; Tracking;
Conference_Titel :
Micro-NanoMechatronics and Human Science (MHS), 2011 International Symposium on
Conference_Location :
Nagoya
Print_ISBN :
978-1-4577-1360-6
DOI :
10.1109/MHS.2011.6102250
