DocumentCode :
2634328
Title :
The simulation of acoustic field in the design of ultrasound driving device for site nano-drug delivery
Author :
Meng, Long ; Jiang, Chun-xiang ; Zheng, Hai-Rong
Author_Institution :
Dept. of Biomed. Eng., Northeastern Univ., Shenyang
fYear :
2008
fDate :
5-8 Dec. 2008
Firstpage :
346
Lastpage :
349
Abstract :
Particle manipulation plays a very important role in many fields, such as ultrasound drug delivery, cell manipulation and trapping molecules. Ultrasonic manipulation, which uses acoustic radiation forces, is a contactless manipulation technique. When the particles suspended in a fluid, the ultrasound radiation forces made the particles concentrate in a designated location. Here it is reported on a simulation for two-dimensional arraying based on the superposition of two in-plane orthogonally oriented standing pressure waves. First, we do the simulation of one-dimensional acoustic field with the FEA software of ANSYS. Then, we got the two-dimensional acoustic field by modify the PZT model. We make the particles concentration when the model was excited with a 14 V amplitude signal at 1.5 MHz.
Keywords :
biological effects of acoustic radiation; drug delivery systems; finite element analysis; nanobiotechnology; ultrasonic devices; ANSYS; FEA software; PZT model; acoustic field; nanodrug delivery; standing pressure waves; ultrasound driving device; Acoustic devices; Acoustical engineering; Biomedical acoustics; Biomedical engineering; Biomedical imaging; Design engineering; Drug delivery; Nanoscale devices; Pharmaceutical technology; Ultrasonic imaging; FEA; PZT; Particle manipulation;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Piezoelectricity, Acoustic Waves, and Device Applications, 2008. SPAWDA 2008. Symposium on
Conference_Location :
Nanjing
Print_ISBN :
978-1-4244-2891-5
Type :
conf
DOI :
10.1109/SPAWDA.2008.4775806
Filename :
4775806
Link To Document :
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