• DocumentCode
    2634328
  • Title

    The simulation of acoustic field in the design of ultrasound driving device for site nano-drug delivery

  • Author

    Meng, Long ; Jiang, Chun-xiang ; Zheng, Hai-Rong

  • Author_Institution
    Dept. of Biomed. Eng., Northeastern Univ., Shenyang
  • fYear
    2008
  • fDate
    5-8 Dec. 2008
  • Firstpage
    346
  • Lastpage
    349
  • Abstract
    Particle manipulation plays a very important role in many fields, such as ultrasound drug delivery, cell manipulation and trapping molecules. Ultrasonic manipulation, which uses acoustic radiation forces, is a contactless manipulation technique. When the particles suspended in a fluid, the ultrasound radiation forces made the particles concentrate in a designated location. Here it is reported on a simulation for two-dimensional arraying based on the superposition of two in-plane orthogonally oriented standing pressure waves. First, we do the simulation of one-dimensional acoustic field with the FEA software of ANSYS. Then, we got the two-dimensional acoustic field by modify the PZT model. We make the particles concentration when the model was excited with a 14 V amplitude signal at 1.5 MHz.
  • Keywords
    biological effects of acoustic radiation; drug delivery systems; finite element analysis; nanobiotechnology; ultrasonic devices; ANSYS; FEA software; PZT model; acoustic field; nanodrug delivery; standing pressure waves; ultrasound driving device; Acoustic devices; Acoustical engineering; Biomedical acoustics; Biomedical engineering; Biomedical imaging; Design engineering; Drug delivery; Nanoscale devices; Pharmaceutical technology; Ultrasonic imaging; FEA; PZT; Particle manipulation;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Piezoelectricity, Acoustic Waves, and Device Applications, 2008. SPAWDA 2008. Symposium on
  • Conference_Location
    Nanjing
  • Print_ISBN
    978-1-4244-2891-5
  • Type

    conf

  • DOI
    10.1109/SPAWDA.2008.4775806
  • Filename
    4775806