Title :
Single-molecule imaging, force measurement and fluorescence observation reveal protein and chromosome dynamics around the nuclear envelope
Author :
Otsuka, S. ; Hirano, Y. ; Takahashi, H. ; Kumeta, M. ; Takeyasu, K. ; Yoshimura, S.H.
Author_Institution :
Kyoto Univ., Kyoto
Abstract :
We have established the techniques of single-molecule imaging and force measurement of various biological samples. By combining these techniques and molecular and cellular biological techniques, we tried to characterize the molecular structure of protein complexes around the nuclear envelope, and the molecular mechanism of protein transport across the nuclear envelope.
Keywords :
cellular biophysics; fluorescence; force; proteins; cellular biological techniques; chromosome dynamics; fluorescence; force measurement; nuclear envelope; protein; single-molecule imaging; Atomic force microscopy; Atomic measurements; Biological cells; Biomembranes; Fluorescence; Force measurement; Glass; Proteins; Temperature; Visualization;
Conference_Titel :
Micro-NanoMechatronics and Human Science, 2007. MHS '07. International Symposium on
Conference_Location :
Nagoya
Print_ISBN :
978-1-4244-1858-9
Electronic_ISBN :
978-1-4244-1858-9
DOI :
10.1109/MHS.2007.4420872
