DocumentCode
2637254
Title
Development of microwave tomography for functional cardiac imaging
Author
Semenov, Serguei Y. ; Posukh, Vitaliy G. ; Bulyshev, Alexander E. ; Williams, Thomas ; Clark, Paula ; Sizov, Yuri E. ; Souvorov, Alexander E. ; Voinov, Boris A.
Author_Institution
Biophys. Lab., Carolinas Med. Center, Charlotte, NC, USA
fYear
2004
fDate
15-18 April 2004
Firstpage
1351
Abstract
We are conducting a research study in development of microwave tomography for functional cardiac imaging. This includes the dielectric spectroscopy of myocardial tissue and imaging experiments. Our findings of dependencies of myocardial dielectric properties from coronary blood flow, ischemia, infarction and hypoxia set up a strong basis for microwave cardiac function imaging in terms of tissue differentiation. The developed three-dimensional (3D) microwave tomographic (MWT) system together with image reconstruction algorithms was used in imaging experiments on excised normal and infarcted canine hearts and intact canines and pigs. Reconstructed images of excised infarcted canine hearts clearly reveal infarcted areas consistent with anatomical slices. Experimental protocols for imaging of intact static canine and swine are underway. Reconstructed images of canine and pig torso were also obtained, indicating the chest cavity with the heart and ventricular chambers.
Keywords
bioelectric phenomena; biological tissues; cardiology; diseases; haemodynamics; image reconstruction; medical image processing; microwave imaging; muscle; tomography; chest cavity; coronary blood flow; dielectric spectroscopy; functional cardiac imaging; hypoxia; image reconstruction algorithm; infarcted canine heart; infarction; intact canines; ischemia; microwave cardiac function imaging; myocardial dielectric property; myocardial imaging; myocardial tissue; pigs; three-dimensional microwave tomography development; tissue differentiation; ventricular chamber; Blood flow; Dielectrics; Electrochemical impedance spectroscopy; Heart; Image reconstruction; Ischemic pain; Microwave imaging; Myocardium; Protocols; Tomography;
fLanguage
English
Publisher
ieee
Conference_Titel
Biomedical Imaging: Nano to Macro, 2004. IEEE International Symposium on
Print_ISBN
0-7803-8388-5
Type
conf
DOI
10.1109/ISBI.2004.1398797
Filename
1398797
Link To Document