• DocumentCode
    2637254
  • Title

    Development of microwave tomography for functional cardiac imaging

  • Author

    Semenov, Serguei Y. ; Posukh, Vitaliy G. ; Bulyshev, Alexander E. ; Williams, Thomas ; Clark, Paula ; Sizov, Yuri E. ; Souvorov, Alexander E. ; Voinov, Boris A.

  • Author_Institution
    Biophys. Lab., Carolinas Med. Center, Charlotte, NC, USA
  • fYear
    2004
  • fDate
    15-18 April 2004
  • Firstpage
    1351
  • Abstract
    We are conducting a research study in development of microwave tomography for functional cardiac imaging. This includes the dielectric spectroscopy of myocardial tissue and imaging experiments. Our findings of dependencies of myocardial dielectric properties from coronary blood flow, ischemia, infarction and hypoxia set up a strong basis for microwave cardiac function imaging in terms of tissue differentiation. The developed three-dimensional (3D) microwave tomographic (MWT) system together with image reconstruction algorithms was used in imaging experiments on excised normal and infarcted canine hearts and intact canines and pigs. Reconstructed images of excised infarcted canine hearts clearly reveal infarcted areas consistent with anatomical slices. Experimental protocols for imaging of intact static canine and swine are underway. Reconstructed images of canine and pig torso were also obtained, indicating the chest cavity with the heart and ventricular chambers.
  • Keywords
    bioelectric phenomena; biological tissues; cardiology; diseases; haemodynamics; image reconstruction; medical image processing; microwave imaging; muscle; tomography; chest cavity; coronary blood flow; dielectric spectroscopy; functional cardiac imaging; hypoxia; image reconstruction algorithm; infarcted canine heart; infarction; intact canines; ischemia; microwave cardiac function imaging; myocardial dielectric property; myocardial imaging; myocardial tissue; pigs; three-dimensional microwave tomography development; tissue differentiation; ventricular chamber; Blood flow; Dielectrics; Electrochemical impedance spectroscopy; Heart; Image reconstruction; Ischemic pain; Microwave imaging; Myocardium; Protocols; Tomography;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Biomedical Imaging: Nano to Macro, 2004. IEEE International Symposium on
  • Print_ISBN
    0-7803-8388-5
  • Type

    conf

  • DOI
    10.1109/ISBI.2004.1398797
  • Filename
    1398797