DocumentCode
2639491
Title
Fabrication of multilayered particles with structured, complex three-dimensional architecture
Author
Tao, Sarah L. ; Desai, Tejal A.
Author_Institution
Dept. of Biomed. Eng., Boston Univ., MA, USA
fYear
2005
fDate
12-15 May 2005
Firstpage
150
Lastpage
151
Abstract
Advances in microelectromechanical systems (MEMS) have allowed the microfabrication of polymeric microparticles and the development of a novel class of controlled delivery devices. Multilayered asymmetric vehicles may be constructed with complex three-dimensional features which may provide the capacity to target cells, promote unidirectional controlled release, and enhance permeation across the intestinal epithelial barrier.
Keywords
drug delivery systems; micromechanical devices; MEMS; controlled delivery devices; intestinal epithelial barrier; microfabrication; multilayered asymmetric vehicles; multilayered particle fabrication; polymeric microparticles; target cells; three-dimensional architecture microelectromechanical systems; Biodegradable materials; Drug delivery; Fabrication; Intestines; Polymers; Reservoirs; Resists; Semiconductor materials; Silicon; Vehicles; microneedles; microparticles;
fLanguage
English
Publisher
ieee
Conference_Titel
Microtechnology in Medicine and Biology, 2005. 3rd IEEE/EMBS Special Topic Conference on
Print_ISBN
0-7803-8711-2
Type
conf
DOI
10.1109/MMB.2005.1548409
Filename
1548409
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