Synchronization control for circadian rhythm of drosophila with flatness-based adaptive control

Author

Kusumi, Tetsuya ; Ohmori, Hiromitsu

Author_Institution

Keio Univ., Tokyo

fYear

2007

fDate

17-20 Sept. 2007

Firstpage

1258

Lastpage

1262

Abstract

Developing molecular biology and system biology, the mechanism of the circadian rhythm in which the inside of the body rhythm of the living thing is ruled is being clarified at the cell level. On the other hand, it is said that various sicknesses are related in the medicine and pharmacology to the disorder of the circadian rhythm. Therefore, it is thought that to restore an altered rhythm is a goal of these therapies. In this paper, we study the 10-states circadian model of Drosophila and propose a close-loop control based on flatness-based adaptive control to achieve circadian rhythm restoration.

Keywords

adaptive control; closed loop systems; medicine; molecular biophysics; synchronisation; zoology; Drosophila; circadian rhythm disorder; circadian rhythm restoration; close-loop control; flatness-based adaptive control; medicine; molecular biology; pharmacology; synchronization control; system biology; Adaptive control; Biological control systems; Biological system modeling; Cancer; Cells (biology); Circadian rhythm; Control systems; Neoplasms; Systems biology; Temperature; Adaptive control; Circadian rhythm; Flatness-based control; Synchronization control; System biology;

fLanguage

English

Publisher

ieee

Conference_Titel

SICE, 2007 Annual Conference

Conference_Location

Takamatsu

Print_ISBN

978-4-907764-27-2

Electronic_ISBN

978-4-907764-27-2

Type

conf

DOI

10.1109/SICE.2007.4421177

Filename

4421177