Title :
Investigation of human hepatoma cell line in microfluidic devices
Author :
Leclerc, Eric ; Griscom, Laurent ; Lepioufle, Bruno ; Guguen-Guillouzo, Christiane ; Corlu, Anne ; Iegallais, C.
Author_Institution :
Lab. of Biomech. & Biomed. Eng., Univ. de Technol. de Compiegne, France
Abstract :
In this paper we have investigated the proliferation of the cell line HepaRG in three types of microfluidic devices. The results demonstrated that the micro geometries play an important role on organisation and proliferation of this type of liver cell.
Keywords :
cellular biophysics; liver; microfluidics; tissue engineering; HepaRG; cell line proliferation; cell organisation; human hepatoma cell line; liver tissue engineering; microfluidic device; Bioreactors; Circuits; Fluid dynamics; Fluid flow; Geometry; Humans; Liver; Microfluidics; Stress; Tissue engineering; liver tissue engineering; microfluidic devices;
Conference_Titel :
Microtechnology in Medicine and Biology, 2005. 3rd IEEE/EMBS Special Topic Conference on
Print_ISBN :
0-7803-8711-2
DOI :
10.1109/MMB.2005.1548482
