Title :
Single red blood cell deformability test using optical trapping in plastic microfluidic chip
Author :
Lee, W.G. ; Park, J. ; Bang, H. ; Chung, S. ; Cho, K. ; Chung, C. ; Han, D.-C. ; Chang, J.K.
Author_Institution :
Sch. of Mech. & Aerosp. Eng., Seoul Nat. Univ., South Korea
Abstract :
In this study, single red blood cell (RBC) deformability test is performed by using optical trapping in poly(dimethylsiloxane) PDMS microfluidic chip. The salient feature of this method is to provide more extensional recovery time of individual RBCs in order to tell the minor difference of RBC deformability between normal and abnormal blood.
Keywords :
biological techniques; biomechanics; blood; cellular biophysics; microfluidics; organic compounds; radiation pressure; abnormal blood; normal blood; optical trapping; plastic microfluidic chip; poly(dimethylsiloxane) microfluidic chip; single red blood cell deformability test; Biomedical optical imaging; Charge carrier processes; Microchannel; Microfluidics; Optical beams; Optical sensors; Plastics; Red blood cells; Shape; Testing; RBC; deformability; optical trapping;
Conference_Titel :
Microtechnology in Medicine and Biology, 2005. 3rd IEEE/EMBS Special Topic Conference on
Print_ISBN :
0-7803-8711-2
DOI :
10.1109/MMB.2005.1548483
