Title :
Atmospheric pressure air plasma treatment of human blood plasma: a kinetic model of coagulation
Author :
Fridman, G. ; Quann, K. ; Peddinghaus, M. ; Fridman, A. ; Balasubramanian, M. ; Gutsol, A. ; Brooks, A. ; Friedman, G.
Author_Institution :
Drexel Plasma Inst., Drexel Univ., Philadelphia, PA
Abstract :
Summary form only given. We observe that floating electrode dielectric barrier discharge (FE-DBD) electric plasma is able to significantly hasten human blood plasma clot formation and influence normal blood protein concentrations. Here, a better understanding of influence of FE-DBD is needed and we propose a first step in this direction - an explanation of influence of FE-DBD on ion concentrations in blood plasma. The presented model compares normal blood coagulation rate with blood undergoing e-plasma treatment by assuming linear relationship between ion concentrations in blood plasma and positive radical production by e-plasma at the surface of blood. Electric plasma is effective in increase of Ca2+ concentration through a redox mechanism: [Ca2+R2-]+H(H2O) - harrkCa|k-Ca[H-R2-] (H2O) -+Ca(H2O) 2-. This mechanism is provided by hydrogen ions generated in air plasma through a sequence of ion-molecular processes
Keywords :
bioelectric phenomena; blood; coagulation; discharges (electric); molecular biophysics; plasma applications; plasma chemistry; plasma collision processes; proteins; reaction kinetics theory; atmospheric pressure air plasma treatment; blood protein concentrations; coagulation; electric plasma; floating electrode dielectric barrier discharge; human blood plasma clot formation; ion concentrations; ion-molecular processes; kinetic model; positive radical production; redox mechanism; Atmospheric modeling; Atmospheric-pressure plasmas; Blood; Coagulation; Dielectrics; Electrodes; Humans; Kinetic theory; Proteins; Water;
Conference_Titel :
Plasma Science, 2006. ICOPS 2006. IEEE Conference Record - Abstracts. The 33rd IEEE International Conference on
Conference_Location :
Traverse City, MI
Print_ISBN :
1-4244-0125-9
DOI :
10.1109/PLASMA.2006.1707310