Title :
Electric field analysis of tumor tissues
Author :
Sree, V. Gowri ; Nandhini, N.A. ; Udayakumar, K. ; Sundararajan, R.
Author_Institution :
Anna Univ., Chennai, India
Abstract :
Electrical-pulse mediated drug delivery is an attractive alternative for malignant tumors that are refractive to conventional therapies, such as surgery, radiation, and chemotherapy. Electric field distribution of tissue/tumor is important for effective treatment of tissues. This paper deals with the electric field distribution study of a tissue model using MAXWELL 3D Simulator. Our results indicate that tumor tissue had lower electric field strength compared to normal cells, which make them susceptible for electrical pulse-mediated drug delivery. This difference could be due to the altered properties of tumor cells compared to normal cells and our results corroborate this.
Keywords :
bioelectric phenomena; biological effects of fields; biomembrane transport; cellular biophysics; drugs; electric field measurement; permeability; physiological models; tumours; MAXWELL 3D Simulator; electric field analysis; electric field distribution; electric field strength; electrical-pulse mediated drug delivery; electroporation; malignant tumors; tissue treatment; tumor cells; tumor tissues; Biomembranes; Brain modeling; Electric fields; Electric potential; Electrodes; Mathematical model; Tumors;
Conference_Titel :
Electrical Insulation and Dielectric Phenomena (CEIDP), 2010 Annual Report Conference on
Conference_Location :
West Lafayette, IN
Print_ISBN :
978-1-4244-9468-2
DOI :
10.1109/CEIDP.2010.5724079