Title :
Spontaneous formation of giant unilamellar vesicles from microdroplets of a polyion complex by focused infrared laser irradiation
Author :
Oana, Hidehiro ; Kishimura, Akihiro ; Yamasaki, Yuichi ; Washizu, Masao ; Kataoka, Kazunori
Author_Institution :
Dept. of Mech. Eng., Univ. of Tokyo, Tokyo, Japan
Abstract :
Spontaneous formation of a giant polymer vesicle from a single micrometer-sized droplet of polyion complex (PIC) of diblock copolymers and its derivative by thermal perturbation, which is achieved by irradiation with a focused infrared laser is presented. The thermal perturbation induces a microphase separation inside of the PIC droplet and the generated water rich phase in the PIC droplet becomes a content of the vesicle and the PIC is deformed into a self-assembled membrane of the vesicle. The size of the giant unilamellar vesicles formed is determined on the basis of the initial size of the PIC droplets.
Keywords :
bio-optics; biological techniques; biomembranes; drops; laser beam applications; phase separation; polymer blends; diblock copolymers; focused infrared laser irradiation; giant polymer vesicle; giant unilamellar vesicles; microdroplets; microphase separation; polyion complex; self-assembled membrane; thermal perturbation; water rich phase; Biological materials; Biomedical engineering; Biomembranes; Lipidomics; Mechanical engineering; Microscopy; Optical materials; Polymers; Production; Solvents;
Conference_Titel :
Micro-NanoMechatronics and Human Science, 2009. MHS 2009. International Symposium on
Conference_Location :
Nagoya
Print_ISBN :
978-1-4244-5094-7
Electronic_ISBN :
978-1-4244-5095-4
DOI :
10.1109/MHS.2009.5352051
