Magnetoencephalography [MEG/MRI/EEG in epilepsy]

When comparing the findings of magnetic source imaging (MSI) with other presurgical evaluations (EEG, MRI and intraoperative ECoG) in temporal lobe epilepsy lobar or even intralobar congruence can be found. The dipolar activity that can be recognized during a spike-wave event is localized in temporal neocortical or mesial regions. Further origin of epileptic activity can be localized by the method of spike averaging. The combination of MEG and MRI helps to build a bridge between morphological and functional localization. For clinical use MSI can serve as a guide for invasive recordings. Additionally it helps to detect functionally important brain regions and can serve as a pointer to discrete lesions in the MRI