Title :
Holding single molecules up to the light: the fluctuating enzymes
Author_Institution :
Harvard Univ., Cambridge, MA, USA
Abstract :
Summary form only given. Single-molecule experiments have shown that an enzyme is a dynamical entity whose conformation and enzymatic rate undergo constant fluctuation over a broad range of time scales.
Keywords :
biochemistry; biological techniques; enzymes; molecular biophysics; biochemical reactivity fluctuations; conformational fluctuation spanning; enzyme molecule; fluctuating enzymes; single molecules; Biochemistry; Biomedical optical imaging; Chemistry; Electrons; Fluctuations; Fluorescence; Optical microscopy;
Conference_Titel :
Quantum Electronics and Laser Science, 2003. QELS. Postconference Digest
Conference_Location :
Baltimore, MD, USA
Print_ISBN :
1-55752-749-0
DOI :
10.1109/QELS.2003.238508
