DocumentCode
2666588
Title
Apertureless near-field fluorescence microscope for biological imaging
Author
Gerton, J.M. ; Lessard, G.A. ; Wade, L.A. ; Quake, S.R.
Author_Institution
Div. of Appl. Phys., California Inst. of Technol., Pasadena, CA, USA
fYear
2003
fDate
6-6 June 2003
Abstract
We measured the optical response of fluorescent beads to sharp metallic and semiconducting probes, revealing several underlying near-field interactions. Our results suggest that /spl sim/10 nanometer optical resolution with spectroscopic chemical sensitivity is possible, and bear strongly on molecular-scale biological imaging.
Keywords
biological techniques; biomedical optical imaging; fluorescence; molecular biophysics; optical microscopy; apertureless fluorescence microscope; biological imaging; fluorescent beads; metallic probes; near-field fluorescence microscope; near-field interactions; optical resolution; semiconducting probes; spectroscopic chemical sensitivity; Biomedical optical imaging; Fluorescence; Image resolution; Microscopy; Nanobioscience; Optical imaging; Optical sensors; Probes; Semiconductivity; Spectroscopy;
fLanguage
English
Publisher
ieee
Conference_Titel
Quantum Electronics and Laser Science, 2003. QELS. Postconference Digest
Conference_Location
Baltimore, MD, USA
Print_ISBN
1-55752-749-0
Type
conf
DOI
10.1109/QELS.2003.238509
Filename
1276035
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