• DocumentCode
    2670078
  • Title

    Sub-diffraction-limit imaging based on the topographic contrast of differential confocal microscopy

  • Author

    Chau-Hwang Lee ; Hui-Yu Chiang ; Hong-Yao Mong

  • Author_Institution
    Inst. of Appl. Sci. & Eng. Res., Acad. Sinica, Taipei, Taiwan
  • fYear
    2003
  • fDate
    6-6 June 2003
  • Abstract
    Using the nanometer topographic sensitivity of differential confocal microscopy, we detect surface features with lateral dimensions smaller than the diffraction limit without fluorescence labeling. Lateral resolution as high as 0.2/spl lambda/ is achieved with maximum-likelihood image restoration.
  • Keywords
    image resolution; image restoration; maximum likelihood estimation; optical microscopy; surface topography; differential confocal microscopy; maximum-likelihood image restoration; subdiffraction-limit imaging; surface features; topographic contrast; Computer vision; Diffraction; Fluorescence; High-resolution imaging; Image resolution; Image restoration; Labeling; Maximum likelihood detection; Microscopy; Surface topography;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Quantum Electronics and Laser Science, 2003. QELS. Postconference Digest
  • Conference_Location
    Baltimore, MD, USA
  • Print_ISBN
    1-55752-749-0
  • Type

    conf

  • DOI
    10.1109/QELS.2003.238527
  • Filename
    1276287