Title :
Electrochemical DNA Sensor Development for Diagnostic Application
Author :
Makai, Dóra ; Gyorffy, A. ; Harsányi, Gábor ; Tulassay, Zsolt
Author_Institution :
Budapest Univ. of Technol. & Econ., Budapest
Abstract :
A miniaturised combined counter and reference electrode is introduced which can be used as a part of a scanning droplet cell for detecting DNA immobilisation on the surface of a gold working electrode by means of a potentiostat. The stability of the reference part of the combined electrode was investigated compared to a saturated calomel electrode. The reference electrode was found stable enough in the first 30 h. The combined electrode was tested in cyclic voltammetric measurements and found suitable for detecting DNA immobilisation on gold surface.
Keywords :
DNA; biosensors; electrochemical sensors; DNA immobilisation; cyclic voltammetric measurements; diagnostic application; electrochemical DNA sensor; reference electrode; saturated calomel electrode; scanning droplet cell; Biomedical electrodes; Counting circuits; DNA; Gold; Kirchhoff´s Law; Probes; Sequences; Stability; Testing; Wire;
Conference_Titel :
Electronics Technology, 2006. ISSE '06. 29th International Spring Seminar on
Conference_Location :
St. Marienthal
Print_ISBN :
1-4244-0551-3
Electronic_ISBN :
1-4244-0551-3
DOI :
10.1109/ISSE.2006.365372
