• DocumentCode
    267755
  • Title

    Highly packed liposome assemblies toward synthetic tissue

  • Author

    Hamano, H. ; Tonooka, Taishi ; Osaki, T. ; Takeuchi, Shoji

  • Author_Institution
    Inst. of Ind. Sci., Univ. of Tokyo, Tokyo, Japan
  • fYear
    2014
  • fDate
    26-30 Jan. 2014
  • Firstpage
    17
  • Lastpage
    19
  • Abstract
    This paper presented an approach for preparation of a highly-packed liposome assembly that implemented lipid bilayer-lipid bilayer contact at the interfaces to mimic a cell-cell connection on living tissues. Cell-sized liposomes were closely packed using our previous technique that allowed monodisperse liposomes arrayed on a substrate. We explored the lipid patterning conditions that would provide a packed structure of the liposomes. By further works, we believe that the assembled structure would be useful for a tissue model.
  • Keywords
    biological tissues; cellular biophysics; lipid bilayers; self-assembly; tissue engineering; cell-cell connection; cell-sized liposomes; highly-packed liposome assembly; lipid bilayer-lipid bilayer contact; lipid patterning conditions; living tissues; monodisperse liposomes; synthetic tissue; tissue model; Arrays; Assembly; Electrostatic discharges; Fluorescence; Lipidomics; Proteins; Substrates;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Micro Electro Mechanical Systems (MEMS), 2014 IEEE 27th International Conference on
  • Conference_Location
    San Francisco, CA
  • Type

    conf

  • DOI
    10.1109/MEMSYS.2014.6765562
  • Filename
    6765562