DocumentCode :
2678903
Title :
DNA Sequence Assembly with Bioinformatics Shotgun Method
Author :
Ho, Michael Shan-Hui ; Hung, Kun-Yu ; Chiu, Chaochang ; Gen, Yu-Shiang
Author_Institution :
Inst. of Electr. Eng., NTPU, Taipei, Taiwan
fYear :
2012
fDate :
28-30 May 2012
Firstpage :
183
Lastpage :
186
Abstract :
DNA sequence assembly is a set of genomic sequences that can be assembled, condensed and oriented in order by applying the sequence homology along with mapping information to create a consensus sequence of a chromosome. The DNA sequence assembly problem has been recognized as NP-hard. In this paper, a newly developed DNA sequence assembly approach along with the bioinformatics shotgun and Hamiltonian path finding methods is introduced and required for exact matches of any DNA sequence to solve worldly well-known DNA sequence assembly problem in polynomial time O(n6).
Keywords :
bioinformatics; polynomials; DNA sequence assembly; Hamiltonian path finding methods; NP-hard problem; bioinformatics shotgun method; chromosome consensus sequence; genomic sequences; mapping information; polynomial time; Adders; Assembly; Bioinformatics; DNA; Electron tubes; Genomics; TV; DNA sequence assembly; Hamiltonian path; NP-hard; bioinformatics computing; shotgun method;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on
Conference_Location :
Macau, Macao
Print_ISBN :
978-1-4577-1987-5
Type :
conf
DOI :
10.1109/iCBEB.2012.157
Filename :
6245086
Link To Document :
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