Title :
Enantioseparation of Peptides with Two Chiral Centers by Capillary Electrophoresis
Author :
Shen, Gangyi ; She, Donglai ; Yu, Wanting ; Li, Shuwen
Author_Institution :
Key Lab. of Chinese Minority Traditional Med., Minzu Univ. of China, Beijing, China
Abstract :
A method has been developed for chiral separation of peptides by capillary electrophoresis. Four peptides including dipeptide and tripeptide with two chiral centers were well separated using the binary selectors of b-CD and SDC. The results indicated that this chiral separation system possesses excellent recognition ability for separation of complex compounds including multi-chiral centers.
Keywords :
capillarity; chirality; electrophoresis; isomerism; organic compounds; SDC; b-CD; binary selectors; capillary electrophoresis; chiral separation system; complex compounds; dipeptide; enantioseparation; multi-chiral centers; peptides; tripeptide; Amino acids; Chemicals; Compounds; Drugs; Educational institutions; Peptides; Capillary electrophoresis; Chiral separation; Peptides with multi-chiral centers;
Conference_Titel :
Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on
Conference_Location :
Macau, Macao
Print_ISBN :
978-1-4577-1987-5
DOI :
10.1109/iCBEB.2012.196
