Title :
Integrated multifunctional fluorescence biosensor based on OLED technology
Author :
Azam, ABM Shafiul ; Boukadoum, Mounir ; Izquierdo, Ricardo ; Acharya, Ashwin ; Packirisamy, Muthukumaran
Author_Institution :
Dept. d´´Inf., Univ. du Quebec a Montreal, Montreal, QC
Abstract :
This paper describes a fluorescence biosensor based on a microfluidic device where an organic LED is used as light emitting source. The device was able to detect fluorescence from a 0.012 mul volume chamber containing 3 ng of donkey anti-sheep IgG (Immunoglobulin G) conjugates tagged with Alexafluor 488 fluorophores. The minimum detectable concentration of the antibody was identified at an enzyme concentration of 200 mug/mL. This result shows that organic LED sources can be used as emitter/photodetector pairs to test biological samples. Based on our results, a multipurpose, integrated biological sensor that can identify and measure the concentration of fluorophore substances is dicussed..
Keywords :
biosensors; fluorescence; microfluidics; microsensors; organic light emitting diodes; Alexafluor 488 fluorophores; OLED technology; antibody concentration; donkey antisheep IgG; fluorophore substance; immunoglobulin G; integrated biological sensor; integrated multifunctional fluorescence biosensor; microfluidic device; Biosensors; Costs; Fluorescence; Immune system; Light emitting diodes; Microfluidics; Optical filters; Optical interferometry; Organic light emitting diodes; Photodetectors;
Conference_Titel :
Circuits and Systems and TAISA Conference, 2008. NEWCAS-TAISA 2008. 2008 Joint 6th International IEEE Northeast Workshop on
Conference_Location :
Montreal, QC
Print_ISBN :
978-1-4244-2331-6
Electronic_ISBN :
978-1-4244-2332-3
DOI :
10.1109/NEWCAS.2008.4606349
