• DocumentCode
    2680746
  • Title

    The Research on Synthesis Methods of Anticoagulants

  • Author

    Ren, Yujie ; Du, Cheng

  • Author_Institution
    Sch. of Chem. & Environ. Eng., Shanghai Inst. of Technol., Shanghai, China
  • fYear
    2012
  • fDate
    28-30 May 2012
  • Firstpage
    622
  • Lastpage
    625
  • Abstract
    This paper summarizes existing anticoagulants mainly from synthesis methods perspective. It covers traditional anticoagulants such as low molecular weight heparins, warfarin, as well as new anticoagulants like argatroban, rivaroxaban, apixaban and direct thrombin inhibitors dabigatran etexilate. This paper also looks forward to future novel anticoagulants using dabigatran etexilate as a lead compound.
  • Keywords
    drugs; anticoagulants; apixaban; argatroban; dabigatran etexilate; heparins; rivaroxaban; synthesis methods; warfarin; Atrial fibrillation; Blood; Compounds; Degradation; Drugs; Inhibitors; Raw materials; anticoagulant; research; synthesis;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on
  • Conference_Location
    Macau, Macao
  • Print_ISBN
    978-1-4577-1987-5
  • Type

    conf

  • DOI
    10.1109/iCBEB.2012.441
  • Filename
    6245196