Title :
Tuning technique for the location of hot spots in proteins using a bandpass notch digital filter
Author :
Ramachandran, Parameswaran ; Lu, Wu-Sheng ; Antoniou, Andreas
Author_Institution :
Dept. of Electr. & Comput. Eng., Univ. of Victoria, Victoria, BC, Canada
Abstract :
A tuning technique is proposed for the location of hot spots in proteins using a bandpass notch (BPN) digital filter. The technique involves tuning the notch frequency of the filter over a small frequency range. To facilitate tuning, a user-friendly graphical interface has been implemented using MATLAB. Simulations have shown that the use of the tuning technique leads to improved hot-spot predictions compared to results obtained using untuned BPN filters.
Keywords :
band-pass filters; biology computing; biomolecular electronics; digital filters; graphical user interfaces; human computer interaction; mathematics computing; notch filters; proteins; tuning; MATLAB; bandpass notch digital filter; notch frequency tuning; protein hot spot location; tuning technique; user-friendly graphical interface; Band pass filters; Biological system modeling; Digital filters; Frequency; IIR filters; MATLAB; Mathematical model; Predictive models; Protein engineering; Tuning;
Conference_Titel :
Genomic Signal Processing and Statistics, 2009. GENSIPS 2009. IEEE International Workshop on
Conference_Location :
Minneapolis, MN
Print_ISBN :
978-1-4244-4761-9
Electronic_ISBN :
978-1-4244-4762-6
DOI :
10.1109/GENSIPS.2009.5174342
