• DocumentCode
    2683075
  • Title

    Numerical Simulation of Descending Curves Sinusoidal Microchannel for Cell Separation System

  • Author

    Ashraf, Muhammad Waseem ; Tayyaba, Shahzadi ; Ishaque, Muhammad ; Afzulpurkar, Nitin

  • Author_Institution
    Sch. of Eng. & Technol., Asian Inst. of Technol. (AIT), Bangkok, Thailand
  • fYear
    2012
  • fDate
    28-30 May 2012
  • Firstpage
    1070
  • Lastpage
    1073
  • Abstract
    This paper deals with a new design of cell separation system. The presented system consists of focusing channel, cell separation device, micro pump, fluid flow sensor, sample storage unit, electronic circuit, central processing unit (CPU), micro controller, cell storage unit and drain collection unit. Finite element software has been used for numerical simulation of descending curves micro channel. The diameters of micro channel curves are 50 μm, 45 μm, 40 μm, 35 μm, 30 μm. Solid particles have been modeled in the channel to analyze the inertial effects during fluid-solid interaction. The diameter of each solid particle is 5 μm. The channel width is 15 μm. The driving pressure of 50 to 300 kPa has been applied on the inlet of micro channel to push the fluid through channel. The inertial forces on the particles inside the channel have been investigated. Presented system and micro channel design can be used for bacterial detection in the blood.
  • Keywords
    bioMEMS; biosensors; cellular biophysics; computational fluid dynamics; finite element analysis; flow sensors; microchannel flow; microcontrollers; microfabrication; micropumps; microsensors; separation; bacterial detection; blood; cell separation device; cell separation system; cell storage unit; central processing unit; descending curves sinusoidal microchannel; drain collection unit; electronic circuit; finite element software; fluid flow sensor; fluid-solid interaction; inertial effects; microcontroller; micropump; numerical simulation; pressure 50 kPa to 300 kPa; sample storage unit; size 5 mum to 50 mum; solid particles; Fluids; Focusing; Microchannel; Numerical simulation; Solids; Sorting; Cell separation system; Computational fluid dynamic (CFD); Microchannels; Microfluidics;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on
  • Conference_Location
    Macao
  • Print_ISBN
    978-1-4577-1987-5
  • Type

    conf

  • DOI
    10.1109/iCBEB.2012.285
  • Filename
    6245312