Title :
Silicon Nanowire Based Immunoassay for the Detection of Prostate Cancer Biomarkers
Author :
Lee, Min-Ho ; Seong, Wookyeong ; Lee, Sangdae ; Kim, Kyungsik
Author_Institution :
Med. IT Convergence Center, Korea Electron. Technol. Inst., Seongnam, South Korea
Abstract :
Recent reports of nanowire based biosensor research showed the promising ability in detection time less than one minute and in detection level down to pg/ml to list a few. In this study, we used newly modified top down based silicon nanowire and measured two types of prostate cancer markers after surface modification. Their dynamic ranges were measured to be 0.184 ~ 17 ng/mL and 0.1 ~ 10 ng/mL, respectively.
Keywords :
biosensors; cancer; chemical sensors; elemental semiconductors; nanofabrication; nanomedicine; nanowires; patient diagnosis; proteins; semiconductor quantum wires; surface treatment; IL-6 antibodies; PSA antibodies; SiNW FET sensor; detection level; detection time; nanowire based biosensor; prostate cancer biomarker detection; prostate specific antigen antibodies; silicon nanowire based immunoassay; surface modification; Fabrication; Immune system; Microfluidics; Nanobioscience; Proteins; Semiconductor device measurement; Silicon; IL-6; PSA; prostate cancer; silicon nanowire;
Conference_Titel :
Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on
Conference_Location :
Macau, Macao
Print_ISBN :
978-1-4577-1987-5
DOI :
10.1109/iCBEB.2012.352
