• DocumentCode
    2685375
  • Title

    The kinetics of beta-amyloid protein polymerization using surface plasmon resonance biosensor

  • Author

    Wu, HsiekTing ; Chien Chou ; Kuo, WerrChuan ; Chien-Yuan Han ; Su-Yun Chiu

  • Author_Institution
    Inst. of Radiol. Sci., Nat.Yang-Ming Univ., Taipei, Taiwan
  • Volume
    2
  • fYear
    2003
  • fDate
    15-19 Dec. 2003
  • Abstract
    In this study, Aβ1-42 aggregation was analyzed, the results show that the association rate constant (ka) is strongly dependent upon the Aβ concentration, but the dissociation rate constant (kd) has no significant change. The Aβ1-42 protein is capable of higher tendency than Aβ1-40 to produce self-assembly.
  • Keywords
    aggregation; association; biochemistry; biosensors; dissociation; molecular biophysics; polymerisation; proteins; self-assembly; surface plasmon resonance; Aβ1-42 aggregation; association rate constant; beta-amyloid protein polymerization; dissociation rate constant; self-assembly; surface plasmon resonance biosensor; Aggregates; Alzheimer´s disease; Biosensors; Kinetic theory; Optical buffering; Optical polymers; Peptides; Plasmons; Proteins; Resonance;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Lasers and Electro-Optics, 2003. CLEO/Pacific Rim 2003. The 5th Pacific Rim Conference on
  • Print_ISBN
    0-7803-7766-4
  • Type

    conf

  • DOI
    10.1109/CLEOPR.2003.1277274
  • Filename
    1277274
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=2685375