DocumentCode :
2685375
Title :
The kinetics of beta-amyloid protein polymerization using surface plasmon resonance biosensor
Author :
Wu, HsiekTing ; Chien Chou ; Kuo, WerrChuan ; Chien-Yuan Han ; Su-Yun Chiu
Author_Institution :
Inst. of Radiol. Sci., Nat.Yang-Ming Univ., Taipei, Taiwan
Volume :
2
fYear :
2003
fDate :
15-19 Dec. 2003
Abstract :
In this study, Aβ1-42 aggregation was analyzed, the results show that the association rate constant (ka) is strongly dependent upon the Aβ concentration, but the dissociation rate constant (kd) has no significant change. The Aβ1-42 protein is capable of higher tendency than Aβ1-40 to produce self-assembly.
Keywords :
aggregation; association; biochemistry; biosensors; dissociation; molecular biophysics; polymerisation; proteins; self-assembly; surface plasmon resonance; Aβ1-42 aggregation; association rate constant; beta-amyloid protein polymerization; dissociation rate constant; self-assembly; surface plasmon resonance biosensor; Aggregates; Alzheimer´s disease; Biosensors; Kinetic theory; Optical buffering; Optical polymers; Peptides; Plasmons; Proteins; Resonance;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Lasers and Electro-Optics, 2003. CLEO/Pacific Rim 2003. The 5th Pacific Rim Conference on
Print_ISBN :
0-7803-7766-4
Type :
conf
DOI :
10.1109/CLEOPR.2003.1277274
Filename :
1277274
Link To Document :
https://search.ricest.ac.ir/dl/search/defaultta.aspx?DTC=49&DC=2685375
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