• DocumentCode
    2694832
  • Title

    Reduction of logical models of regulatory networks yields insight into dynamical properties

  • Author

    Chaouiya, Claudine ; Naldi, Aurélien ; Remy, Elisabeth ; Thieffry, Denis

  • Author_Institution
    Inst. Gulbenkian de Cienc., Oeiras, Portugal
  • fYear
    2010
  • fDate
    8-10 Sept. 2010
  • Firstpage
    524
  • Lastpage
    529
  • Abstract
    The logical formalism is a convenient framework to qualitatively model regulatory networks for which detailed quantitative information is barely available. In this discrete framework, network behaviours are usually represented by means of state transition graphs. However, as network sizes increase, state transition graphs often become too large to be effectively constructed, let alone analysed.
  • Keywords
    delays; discrete systems; graph theory; reduced order systems; delay constraint; discrete framework; dynamical properties; logical formalism; logical model reduction; network behaviour; network size; nonterminal strongly connected components; regulatory network; segment-polarity module; state transition graph; transient oscillation; Biological system modeling; Context; Integrated circuit modeling; Oscillators; Regulators; Trajectory; Transient analysis;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Control Applications (CCA), 2010 IEEE International Conference on
  • Conference_Location
    Yokohama
  • Print_ISBN
    978-1-4244-5362-7
  • Electronic_ISBN
    978-1-4244-5363-4
  • Type

    conf

  • DOI
    10.1109/CCA.2010.5611238
  • Filename
    5611238