DocumentCode
2694832
Title
Reduction of logical models of regulatory networks yields insight into dynamical properties
Author
Chaouiya, Claudine ; Naldi, Aurélien ; Remy, Elisabeth ; Thieffry, Denis
Author_Institution
Inst. Gulbenkian de Cienc., Oeiras, Portugal
fYear
2010
fDate
8-10 Sept. 2010
Firstpage
524
Lastpage
529
Abstract
The logical formalism is a convenient framework to qualitatively model regulatory networks for which detailed quantitative information is barely available. In this discrete framework, network behaviours are usually represented by means of state transition graphs. However, as network sizes increase, state transition graphs often become too large to be effectively constructed, let alone analysed.
Keywords
delays; discrete systems; graph theory; reduced order systems; delay constraint; discrete framework; dynamical properties; logical formalism; logical model reduction; network behaviour; network size; nonterminal strongly connected components; regulatory network; segment-polarity module; state transition graph; transient oscillation; Biological system modeling; Context; Integrated circuit modeling; Oscillators; Regulators; Trajectory; Transient analysis;
fLanguage
English
Publisher
ieee
Conference_Titel
Control Applications (CCA), 2010 IEEE International Conference on
Conference_Location
Yokohama
Print_ISBN
978-1-4244-5362-7
Electronic_ISBN
978-1-4244-5363-4
Type
conf
DOI
10.1109/CCA.2010.5611238
Filename
5611238
Link To Document