Title :
Development of a probe for simultaneous collection of optical and NMR spectra in vivo
Author :
McNichols, Roger J. ; Coté, Gerard L. ; Wright, Steven M.
Author_Institution :
Dept. of Bioeng., Texas A&M Univ., College Station, TX, USA
fDate :
30 Oct-2 Nov 1997
Abstract :
In this paper, we report the development of a probe for simultaneous acquisition of NMR and optical fluorescence spectra in vivo. An array of small radio frequency (RF) surface coils will be used with time-domain multiplexing (TDM) in conjunction with multiple fiber-optic probes imaged with a CCD based optical multichannel analyzer (OMA). We demonstrate that an array of coils can be used to tailor the field of view (FOV) of the experiment to a specific region of interest (ROI) without the use of gradients
Keywords :
CCD image sensors; NMR spectrometers; bio-optics; biological NMR; biological techniques; biomedical NMR; biomedical equipment; coils; fibre optic sensors; fluorescence spectroscopy; CCD based optical multichannel analyzer; NMR spectra in vivo; array of RF surface coils; combined optical/NMR probe; field of view; in vivo biological studies; multiple fiber-optic probes; optical fluorescence spectra in vivo; simultaneous acquisition; specific region of interest; time-domain multiplexing; turtle heart; Charge coupled devices; Coils; Fluorescence; In vivo; Nuclear magnetic resonance; Optical arrays; Probes; Radio frequency; Time division multiplexing; Time domain analysis;
Conference_Titel :
Engineering in Medicine and Biology Society, 1997. Proceedings of the 19th Annual International Conference of the IEEE
Conference_Location :
Chicago, IL
Print_ISBN :
0-7803-4262-3
DOI :
10.1109/IEMBS.1997.756792
