Development of a probe for simultaneous collection of optical and NMR spectra in vivo

Author

McNichols, Roger J. ; Coté, Gerard L. ; Wright, Steven M.

Author_Institution

Dept. of Bioeng., Texas A&M Univ., College Station, TX, USA

Volume

6

fYear

1997

fDate

30 Oct-2 Nov 1997

Firstpage

2365

Abstract

In this paper, we report the development of a probe for simultaneous acquisition of NMR and optical fluorescence spectra in vivo. An array of small radio frequency (RF) surface coils will be used with time-domain multiplexing (TDM) in conjunction with multiple fiber-optic probes imaged with a CCD based optical multichannel analyzer (OMA). We demonstrate that an array of coils can be used to tailor the field of view (FOV) of the experiment to a specific region of interest (ROI) without the use of gradients

Keywords

CCD image sensors; NMR spectrometers; bio-optics; biological NMR; biological techniques; biomedical NMR; biomedical equipment; coils; fibre optic sensors; fluorescence spectroscopy; CCD based optical multichannel analyzer; NMR spectra in vivo; array of RF surface coils; combined optical/NMR probe; field of view; in vivo biological studies; multiple fiber-optic probes; optical fluorescence spectra in vivo; simultaneous acquisition; specific region of interest; time-domain multiplexing; turtle heart; Charge coupled devices; Coils; Fluorescence; In vivo; Nuclear magnetic resonance; Optical arrays; Probes; Radio frequency; Time division multiplexing; Time domain analysis;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1997. Proceedings of the 19th Annual International Conference of the IEEE

Conference_Location

Chicago, IL

ISSN

1094-687X

Print_ISBN

0-7803-4262-3

Type

conf

DOI

10.1109/IEMBS.1997.756792

Filename

756792