Development of the pulse-electrochemotherapy system and application for tumor treatment

Author

Zhu, Fansan ; Lin, Jiarui ; Tan, Shu ; Zhou, Yuli

Author_Institution

Dept. of Bioeng., Huazhong Univ. of Sci. & Technol., Wuhan, China

Volume

6

fYear

1997

fDate

30 Oct-2 Nov 1997

Firstpage

2424

Abstract

In this paper, a new electrochemotherapy system for tumor treatment is described. The treatment system can produce electrical energy output in two current forms: direct current (DC) and pulses. In order to be electrically safe, the system supplies the function of output synchronization pulse with R waveform. In this study, fifteen patients with esophageal cancer were treated using this system. The results show that total effectiveness, which includes CR and PR, is 73.4%. We also discuss some important parameters of ECT for tumor treatment in animal experiments and clinical trials

Keywords

bioelectric phenomena; biological effects of fields; biomedical electrodes; biomedical electronics; cancer; patient treatment; pulse generators; safety; tumours; R waveform; electrical energy output; electrical safety; oesophageal cancer; output synchronization pulse; pulse generator; pulse-electrochemotherapy system; tumour treatment; Animals; Cancer; Chemical technology; Clinical trials; Drugs; Electrical capacitance tomography; Electrodes; Esophagus; Medical treatment; Neoplasms;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 1997. Proceedings of the 19th Annual International Conference of the IEEE

Conference_Location

Chicago, IL

ISSN

1094-687X

Print_ISBN

0-7803-4262-3

Type

conf

DOI

10.1109/IEMBS.1997.756812

Filename

756812