Simulation studies on the dynamics of diabetes mellitus

Author

Erzen, Fetanet Ceylan ; Birol, Gülnur ; Çinar, Ali

Author_Institution

Dept. of Chem. & Environ. Eng., Illinois Inst. of Technol., Chicago, IL, USA

fYear

2000

fDate

2000

Firstpage

231

Lastpage

235

Abstract

Glucose-insulin interaction in an insulin-dependent diabetic patient has been simulated using an overall and a detailed model based on pharmacokinetic diagrams of insulin and glucose. Both models are capable of predicting the blood glucose and insulin levels, total glucose uptake and the renal glucose excretion. The simulator is integrated with a graphical user interface to provide a user-friendly environment. The package may be used to perform virtual experiments with various characteristics, diet and exercise conditions

Keywords

biochemistry; blood; digital simulation; diseases; graphical user interfaces; medical computing; organic compounds; physiological models; blood glucose level; blood insulin level; detailed model; diabetes mellitus dynamics; diet; exercise conditions; glucose-insulin interaction; insulin-dependent diabetic patient; overall model; pharmacokinetic diagrams; renal glucose excretion; total glucose uptake; user-friendly environment; virtual experiments; Biochemistry; Blood; Cells (biology); Chemical technology; Diabetes; Insulin; Liver; Mathematical model; Pancreas; Sugar;

fLanguage

English

Publisher

ieee

Conference_Titel

Bio-Informatics and Biomedical Engineering, 2000. Proceedings. IEEE International Symposium on

Conference_Location

Arlington, VA

Print_ISBN

0-7695-0862-6

Type

conf

DOI

10.1109/BIBE.2000.889612

Filename

889612