DocumentCode
270379
Title
Cell membrane electroporation-Part 3: the equipment
Author
RebersÌŒek, M. ; Miklavcic, Damijan ; Bertacchini, C. ; Sack, M.
Author_Institution
Lab. of Biocybernetics, Univ. of Ljubljana, Ljubljana, Slovenia
Volume
30
Issue
3
fYear
2014
fDate
May-June 2014
Firstpage
8
Lastpage
18
Abstract
As described in Part 1, a cell membrane can be made permeable to various molecules by carrying out a procedure called electroporation [1]. This procedure is being successfully used in biology, biotechnology, and medicine [2], [3]. It requires electroporators and electrodes. An electroporator generates short HV pulses of specific shape, amplitude, duration, number, and repetition frequency [4], and the pulses are applied to the target cells or load through the electrodes [5]. The energy delivered to the load is governed by the number of pulses and the pulse voltage, current, and duration. In biomedical applications that energy can be several joules; in biotechnology, where electroporation is used for treatment of agricultural products and water, it can be several kilojoules.
Keywords
biomedical electrodes; biomembranes; cellular biophysics; high-voltage techniques; molecular biophysics; pulse generators; agricultural products treatment; biology; biomedical application; biotechnology; cell membrane electroporation; electrodes; electroporator; medicine; pulse current; pulse duration; pulse voltage; short HV pulse generation; water treatment; Cell membranes; Electrodes; Generators; Impedance; Optical switches; Power transmission lines; Pulse generation; Safety; electrode; electroporator; pulse generator; safety standard;
fLanguage
English
Journal_Title
Electrical Insulation Magazine, IEEE
Publisher
ieee
ISSN
0883-7554
Type
jour
DOI
10.1109/MEI.2014.6804737
Filename
6804737
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