Title :
The design of electrode-array for monitoring the cellular bioimpedance
Author :
Lu, Yi-yu ; Huang, Ji-Jer ; Cheng, Kuo-Sheng
Author_Institution :
Electr. Eng. Dept., Nat. Cheng Kung Univ. (NCKU), Tainan, Taiwan
Abstract :
To real-time monitor the cell viability an important task in cell culturing associated applications. The bioimpedance spectroscopy is one of the useful techniques for this study. In this paper, a culture dish with an electrode-array is designed for the bioimpedance based cellular characterization. The electrode-array containing 32 electrodes is firstly fabricated using the Micro-Electro-Mechanical-System (MEMS) technology, and then attached on the inner side of culture dish. Two types of current patterns of so-called the opposite and adjacent current patterns are then applied for the performance assessment of the proposed electrode-array. From the experimental results, the gap between the electrodes and the width of electrodes are shown to be very homogenous. The proposed culture dish with an electrode-array is demonstrated to be feasible in bioimpedance spectroscopic measurement of cellular electrical property.
Keywords :
bioMEMS; bioelectric phenomena; biomedical electrodes; cellular biophysics; MEMS technology; cell culturing; cell viability; cellular bioimpedance monitoring; electrode array; microelectromechanical system; Bioimpedance; Biomedical engineering; Biomedical measurements; Biomedical monitoring; Biopsy; Electric variables measurement; Electrodes; Impedance; Micromechanical devices; Spectroscopy; Bioimpedance spectroscopy; Electrical biopsy; Electrode array;
Conference_Titel :
Industrial Electronics & Applications, 2009. ISIEA 2009. IEEE Symposium on
Conference_Location :
Kuala Lumpur
Print_ISBN :
978-1-4244-4681-0
Electronic_ISBN :
978-1-4244-4683-4
DOI :
10.1109/ISIEA.2009.5356375