Wide bandwidth cell impedance spectroscopy based on digital auto balancing bridge method

Author

Li, Nan ; Xu, Hui ; Zhou, Zhou ; Sun, Zhaolin ; Xu, Xin ; Wang, Wei

Author_Institution

Sch. of Electron. Sci. & Eng., Nat. Univ. of Defense Technol., Changsha, China

fYear

2011

fDate

10-12 Nov. 2011

Firstpage

53

Lastpage

56

Abstract

This paper presented the design of a cell impedance spectroscopy which based on a digital auto balancing bridge method. The hardware architecture of the system mainly consists of a reference source, a variable source, a null detector and a FPGA. DSP algorithms such as CORDIC-based direct digital synthesis and LMS-based auto balancing algorithm were discussed in detail. The simulation results show that the system has good performance from low frequency up to 10 MHz. Profiting from the cost efficiency and high flexibility of digital device, it suitable for EIS application in cell-level research.

Keywords

bioelectric potentials; biomedical electronics; biomedical engineering; cellular biophysics; digital signal processing chips; electric impedance; electric impedance imaging; field programmable gate arrays; least mean squares methods; medical computing; CORDIC based direct digital synthesis; DSP algorithm; FPGA; LMS based auto balancing algorithm; cell level research; digital auto balancing bridge method; digital device; electrical impedance spectroscopy; hardware architecture; least mean square algorithm; null detector; wide bandwidth cell impedance spectroscopy; Algorithm design and analysis; Bridge circuits; Computer architecture; Field programmable gate arrays; Frequency measurement; Impedance; Microprocessors;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Circuits and Systems Conference (BioCAS), 2011 IEEE

Conference_Location

San Diego, CA

Print_ISBN

978-1-4577-1469-6

Type

conf

DOI

10.1109/BioCAS.2011.6107725

Filename

6107725