Title :
A new method for the quantitative study of neurotransmission
Author :
Frenoux, E. ; Barra, V. ; Boire, J.-Y. ; Habert, Marie-Odile
Author_Institution :
Fac. de Medicine, ERIM-CENTI, Clermont-Ferrand, France
Abstract :
We propose here a new method for the automatic quantification of neurotransmission using data fusion. The process uses a magnetic resonance image as anatomical reference and a single photon emission computed tomography image of the same patient for functional information. Once both acquisitions are coregistered, the process is divided in two steps: first, structures of interest are automatically segmented using a data fusion-based algorithm, then the masks obtained are used to compute functional indexes in the SPECT. Both steps of the process are now validated and we plan to apply it as a tool for differential diagnosis in a wide range of pathologies.
Keywords :
biomedical MRI; brain; image registration; image segmentation; medical image processing; neurophysiology; single photon emission computed tomography; SPECT; automatic quantification; data fusion-based algorithm; functional indexes; functional information; image coregistration; image segmentation; magnetic resonance image; neurotransmission; single photon emission computed tomography image; Data mining; Image segmentation; Magnetic cores; Magnetic resonance; Magnetic resonance imaging; Neurotransmitters; Parkinson´s disease; Pathology; Single photon emission computed tomography; Spatial resolution;
Conference_Titel :
Engineering in Medicine and Biology Society, 2003. Proceedings of the 25th Annual International Conference of the IEEE
Print_ISBN :
0-7803-7789-3
DOI :
10.1109/IEMBS.2003.1279926