Evaluation of multimodal imaging approaches for combined pre- and intraoperative imaging in oncology

New methods with higher sensitivity and specificity are required for effective image-guided surgery. We have developed a multimodal strategy that gives the same intraoperative detection accuracy as is currently achieved with common preoperative imaging procedures. Based on our own results with sentinel lymph node imaging and the use of bracketing marker seeds, the value of multimodal imaging approaches for a combined pre-and intraoperative application is evaluated.