Title :
Experimental validation and sensitivity analysis for CFD simulations of cerebral aneurysms
Author :
Sun, Qi ; Groth, Alexandra ; Bertram, Matthias ; Waechter, Irina ; Bruijns, Tom ; Hermans, Roel ; Pereira, Vitor Mendes ; Brina, Olivier ; Aach, Til
Abstract :
In this work, by exploiting a phantom aneurysm model, we illustrate the correlation between experimental data and computational fluid dynamics (CFD) simulation results under well controlled conditions. This is difficult to achieve with clinical patient cases where several uncertainties are present. Quantitative measures are defined for CFD validation by virtual angiography. In addition, a parametric study has been carried out to systematically investigate the sensitivity of current measuring technique on the flow pattern.
Keywords :
blood flow measurement; blood vessels; brain; computational fluid dynamics; diagnostic radiography; medical disorders; neurophysiology; phantoms; physiological models; CFD simulations; cerebral aneurysms; computational fluid dynamics simulation; flow pattern; phantom aneurysm model; sensitivity analysis; virtual angiography; Analytical models; Aneurysm; Angiography; Computational fluid dynamics; Computational modeling; Current measurement; Fluid flow control; Imaging phantoms; Parametric study; Sensitivity analysis; Aneurysm; CFD simulation; sensitivity analysis; time intensity curve; validation; virtual angiography;
Conference_Titel :
Biomedical Imaging: From Nano to Macro, 2010 IEEE International Symposium on
Conference_Location :
Rotterdam
Print_ISBN :
978-1-4244-4125-9
Electronic_ISBN :
1945-7928
DOI :
10.1109/ISBI.2010.5490170