Photon attenuation correction in whole-body PET/MRI using tissue classification

Author

Martinez-Möller, Axel ; Souvatzoglou, Michael ; Nekolla, Stephan G.

Author_Institution

Nuklearmed. Klinik, Tech. Univ. Munchen, Munich, Germany

fYear

2010

fDate

14-17 April 2010

Firstpage

1061

Lastpage

1062

Abstract

A challenge for hybrid PET/MRI imaging is the determination of the photon attenuation map to correct the acquired PET data. Segmentation of adapted MRI sequence data in four tissue classes (background, lungs, fat, and soft tissue) is proposed and evaluated using data from 35 PET/CT whole-body oncological examinations as well as two PET/CT and MRI examinations from the same patients. When reconstructing with the segmented attenuation map, small differences in tumor uptake were observed mainly for osseous lesions, but did not change the clinical interpretation in any case. The method appears to be viable for clinical use.

Keywords

biological tissues; biomedical MRI; cancer; image classification; image reconstruction; image segmentation; image sequences; lung; medical image processing; positron emission tomography; adapted MRI sequence; fat; hybrid PET/MRI imaging; image reconstruction; image segmentation; lungs; oncology; photon attenuation correction; soft tissue; tissue classification; Attenuation; Biological tissues; Computed tomography; Image reconstruction; Image segmentation; Lesions; Lungs; Magnetic resonance imaging; Neoplasms; Whole-body PET; Attenuation Correction; Magnetic Resonance; Positron Emission Tomography;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Imaging: From Nano to Macro, 2010 IEEE International Symposium on

Conference_Location

Rotterdam

ISSN

1945-7928

Print_ISBN

978-1-4244-4125-9

Electronic_ISBN

1945-7928

Type

conf

DOI

10.1109/ISBI.2010.5490173

Filename

5490173