DocumentCode :
272233
Title :
A versatile and experimentally validated finite element model to assess the accuracy of shear wave elastography in a bounded viscoelastic medium
Author :
Caenen, Annette ; Shcherbakova, Darya ; Verhegghe, Benedict ; Papadacci, Clément ; Pernot, Mathieu ; Segers, Patrick ; Swillens, Abigaïl
Author_Institution :
IBiTech-bioMMeda, Ghent Univ., Ghent, Belgium
Volume :
62
Issue :
3
fYear :
2015
fDate :
Mar-15
Firstpage :
439
Lastpage :
450
Abstract :
The feasibility of shear wave elastography (SWE) in arteries for cardiovascular risk assessment remains to be investigated as the artery´s thin wall and intricate material properties induce complex shear wave (SW) propagation phenomena. To better understand the SW physics in bounded media, we proposed an in vitro validated finite element model capable of simulating SW propagation, with full flexibility at the level of the tissue´s geometry, material properties, and acoustic radiation force. This computer model was presented in a relatively basic set-up, a homogeneous slab of gelatin-agar material (4.35 mm thick), allowing validation of the numerical settings according to actual SWE measurements. The resulting tissue velocity waveforms and SW propagation speed matched well with the measurement: 4.46 m/s (simulation) versus 4.63 ± 0.07 m/s (experiment). Further, we identified the impact of geometrical and material parameters on the SW propagation characteristics. As expected, phantom thickness was a determining factor of dispersion. Adding viscoelasticity to the model augmented the estimated wave speed to 4.58 m/s, an even better match with the experimental determined value. This study demonstrated that finite element modeling can be a powerful tool to gain insight into SWE mechanics and will in future work be advanced to more clinically relevant settings.
Keywords :
biomedical ultrasonics; blood vessels; cardiovascular system; elastic waves; finite element analysis; phantoms; viscoelasticity; acoustic radiation force; artery thin wall; cardiovascular risk assessment; finite element model; gelatin-agar material; phantom thickness; shear wave elastography accuracy; shear wave elastography measurement; shear wave elastography mechanics; shear wave physics; shear wave propagation characteristics; shear wave propagation phenomena; size 4.35 mm; tissue geometry; tissue velocity waveform; velocity 4.46 m/s; velocity 4.58 m/s; viscoelastic medium; viscoelasticity; Acoustics; Computational modeling; Data models; Force; Materials; Numerical models; Phantoms;
fLanguage :
English
Journal_Title :
Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on
Publisher :
ieee
ISSN :
0885-3010
Type :
jour
DOI :
10.1109/TUFFC.2014.006682
Filename :
7055439
Link To Document :
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