Title :
KI-67 hot-spots detection on glioblastoma tissue sections
Author :
Lopez, Xavier Moles ; Debeir, Olivier ; Maris, Calliope ; Roland, Isabelle ; Salmon, Isabelle ; Decaestecker, Christine
Author_Institution :
Lab. of Image Synthesis & Anal. (LISA), Univ. Libre de Bruxelles, Brussels, Belgium
Abstract :
Glioblastomas are very aggressive cerebral tumors which are characterized by strong proliferative activity which is often assessed using the Ki-67 staining method. We propose a novel clustering method that exhibits high performance to detect Ki-67 hot-spots on immunohistochemical slides of glioblastomas.
Keywords :
biochemistry; brain; cancer; cellular biophysics; medical image processing; pattern clustering; tumours; Ki-67 hot-spot detection; Ki-67 staining method; cerebral tumors; clustering method; glioblastomas; immunohistochemistry; proliferative activity; Carbon capture and storage; Character generation; Clustering algorithms; Couplings; Image color analysis; Immune system; Labeling; Neoplasms; Shape; Topology; biomarker; clustering; immunohistochemistry; staining;
Conference_Titel :
Biomedical Imaging: From Nano to Macro, 2010 IEEE International Symposium on
Conference_Location :
Rotterdam
Print_ISBN :
978-1-4244-4125-9
Electronic_ISBN :
1945-7928
DOI :
10.1109/ISBI.2010.5490393
