Editorial: Part 2: Network construction and mining for systems biology

The molecular networks provide the context in which the molecules interact with each other and can therefore help us understand the functions of these molecules. Unfortunately, the current knowledge about molecular networks is far from complete. It is time consuming and expensive to screen possible interactions between distinct molecules in a lab. Furthermore, the current interactomes deposited in popular public databases are generally static snapshots of the dynamic molecular interactions that change with time. Therefore, some computational approaches have been proposed for reverse-engineering andmining the interactomes.