Title :
Assessment of knee osteoarthritis by bioelectrical impedance
Author :
Alvarenga, R.L. ; Souza, M.N.
Author_Institution :
Biomed. Eng. Program, Federal Univ. of Rio de Janeiro, Brazil
Abstract :
This study aimed to investigate the application of a bioimpedance spectroscopy technique, based on the current response to a voltage step excitation, as a diagnosis tool to the knee osteoarthritis problem. Up to now, 14 individuals (4 men and 10 women) have participated of the study, being grouped as health subjects (NG) and subjects with knee osteoarthritis diagnosis (OG). A total of 28 bioelectrical impedance measurements in the knee joint have been made. The average value of the knee intracellular resistance was of 281 82.6 Q in the NG and 143±33.9 Q in the OG. Besides this difference is statistically significant (p<0.01) between the groups, ratio between the intracellular and extracellular resistances, that was of the 1.6±0.5 in the NG and 0.8±0.2 in the OG, seems to be a better index to be used in the diagnosis. The results of this study suggest that the proposed method of bioelectrical impedance evaluation, when applied the diagnosis of the knee, is a valid method to determine the inflammatory pathological conditions of this joint.
Keywords :
bioelectric phenomena; biomechanics; bone; cellular biophysics; diseases; electric resistance measurement; orthopaedics; patient diagnosis; bioelectrical impedance analysis; bioelectrical impedance evaluation; bioimpedance spectroscopy technique; diagnosis tool; health subjects; inflammatory pathological condition; knee assessment; knee intracellular resistance; knee osteoarthritis diagnosis; osteoarthritis; voltage step excitation; Bioelectric phenomena; Bioimpedance; Extracellular; Immune system; Impedance measurement; Knee; Osteoarthritis; Pathology; Spectroscopy; Voltage;
Conference_Titel :
Engineering in Medicine and Biology Society, 2003. Proceedings of the 25th Annual International Conference of the IEEE
Print_ISBN :
0-7803-7789-3
DOI :
10.1109/IEMBS.2003.1280802