Title :
Studying mammalian neurons in vitro with multielectrode arrays
Author_Institution :
Dept. of Phys., Math. & Astron., California Inst. of Technol., Pasadena, CA, USA
Abstract :
The basic principles for recording and stimulation with extracellular electrodes are described, and how they relate to the use of multielectrode arrays, MEAs, for studies of neural networks in culture. The main engineering issues for building arrays are described, and some examples are given of their use. The "neurochip" which has evolved from standard arrays is described, as well as other possible future developments.
Keywords :
arrays; biomedical electrodes; cellular biophysics; microelectrodes; neural chips; cultures; extracellular electrodes; in vitro; mammalian neurons; multielectrode arrays; neural networks; neurochip; Astronomy; Biological neural networks; Electrodes; Extracellular; In vitro; Mathematics; Medium voltage; Nerve fibers; Neurons; Physics;
Conference_Titel :
Engineering in Medicine and Biology Society, 2003. Proceedings of the 25th Annual International Conference of the IEEE
Print_ISBN :
0-7803-7789-3
DOI :
10.1109/IEMBS.2003.1280958