Title :
Genetic data acquirement, construction and analysis based on microarray technology
Author_Institution :
Nat. Lab. of Molecular & Biomolecular Electron., Southeast Univ., Nanjing, China
Abstract :
Several novel microarray technology platforms to be applied to acquire both genetic and epigenetic data from biological systems have been developed. Genetic database and the related bioinformatics analytic tools are being constructed. Here, some on-going projects related to bioinformatics analysis based on the microarray technology, such as such as the high density microarray design, combinational analyses of the data based on microarrays for gene expressions, methylation of CG islands, trans-factor protein level and mutation detection, and the disease related SNPs in human genomes are presented.
Keywords :
biochemistry; biology computing; cellular biophysics; combinatorial mathematics; data analysis; database management systems; diseases; genetics; molecular biophysics; polymorphism; proteins; CG islands; bioinformatics analysis; biological systems; combinational analysis; disease; epigenetic data; gene expressions; genetic data acquirement; genetic data analysis; genetic data construction; genetic database; human genomes; methylation; microarray technology; mutation detection; single nucleotide polymorphism; trans-factor protein level; Bioinformatics; Biological systems; Character generation; Data analysis; Databases; Diseases; Gene expression; Genetic mutations; Humans; Proteins; Bioinformatics; SNPs; high density microarray design;
Conference_Titel :
Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE
Conference_Location :
San Francisco, CA
Print_ISBN :
0-7803-8439-3
DOI :
10.1109/IEMBS.2004.1403836
