Title :
PRISM: protein integration of sequence metrics
Author :
Addison, E.R. ; Hobbs, E.T.
Author_Institution :
LLC, Columbia, MA, USA
Abstract :
PRISM is a comprehensive method for predicting protein sequence structure and function by providing a mechanism to combine information from numerous structure and function prediction tools into one comprehensive view. It uses an evidential reasoning calculus to combine information provided from multiple sources into a consensus solution. The output of PRISM is a comprehensive one stop shop report of all information about a given known or novel protein.
Keywords :
biology computing; molecular biophysics; proteins; PRISM software system; function prediction tool; protein sequence structure; Amino acids; Databases; Diseases; Hidden Markov models; Hydrogen; Organisms; Prediction methods; Protein sequence; Software systems; function; protein; sequence; structure;
Conference_Titel :
Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE
Conference_Location :
San Francisco, CA
Print_ISBN :
0-7803-8439-3
DOI :
10.1109/IEMBS.2004.1403848
