Title :
Clustering protein-protein docking predictions
Author :
Tong, W. ; Weng, Z.
Author_Institution :
Dept. of Biomed. Eng., Boston Univ., MA, USA
Abstract :
We describe a clustering algorithm for improving protein-protein docking predictions. The algorithm was applied to two sets of predictions for 36 test cases, one set generated with a rigid-body docking algorithm ZDOCK, and the other set with ZDOCK followed by a refinement algorithm RDOCK, and consistent improvement was observed.
Keywords :
biology computing; molecular biophysics; pattern clustering; proteins; RDOCK; ZDOCK; clustering algorithm; protein-protein docking; refinement algorithm; rigid-body docking algorithm; Accuracy; Biological systems; Clustering algorithms; Computational modeling; Crystallography; Nuclear magnetic resonance; Prediction algorithms; Predictive models; Proteins; Testing; Protein docking; clustering; refinement;
Conference_Titel :
Engineering in Medicine and Biology Society, 2004. IEMBS '04. 26th Annual International Conference of the IEEE
Conference_Location :
San Francisco, CA
Print_ISBN :
0-7803-8439-3
DOI :
10.1109/IEMBS.2004.1403850
