DocumentCode
2736198
Title
The alternation of cellular viscoelasticity and cellular response in endothelial cell under hyperglycemia
Author
Jang, Hyunyoung ; Targovnik, Jerome ; Massia, Stephen
Author_Institution
Dept. of Bioeng., Arizona State Univ., Tucson, AZ, USA
Volume
4
fYear
2003
fDate
17-21 Sept. 2003
Firstpage
3876
Abstract
To investigate the effect of hyperglycemia on cellular viscoelastic properties in bovine endothelial cells (BECs), rheology was employed. We found that the viscoelastic properties of BECs were altered under high glucose environment. Also high glucose suppressed the formation of actin filament and focal contacts.
Keywords
biomechanics; blood vessels; cellular biophysics; diseases; haemorheology; molecular biophysics; proteins; sugar; viscoelasticity; actin filament; bovine endothelial cells; cellular response; cellular viscoelasticity; endothelial cell; glucose environment; hyperglycemia; rheology; Atherosclerosis; Biomedical engineering; Bovine; Elasticity; Frequency; Mechanical factors; Pathogens; Rheology; Sugar; Viscosity;
fLanguage
English
Publisher
ieee
Conference_Titel
Engineering in Medicine and Biology Society, 2003. Proceedings of the 25th Annual International Conference of the IEEE
ISSN
1094-687X
Print_ISBN
0-7803-7789-3
Type
conf
DOI
10.1109/IEMBS.2003.1281011
Filename
1281011
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