Title :
Invited: Metabolic network alignments
Author :
Zelikovsky, Alex
Author_Institution :
Dept. of Comput. Sci., Georgia State Univ., Atlanta, GA, USA
Abstract :
A general network alignment problem: a pathway forms a pattern and a cellular network (usually from another species) forms the text, and how to find the best correspondence between the text and the pattern, is investigated. A representation of metabolic network/pathway by a graph in which vertices are labeled by enzymes which they represent and each of its directed edges connects enzymes catalyzing consecutive reactions, is also discussed.
Keywords :
catalysis; cellular biophysics; chemical reactions; enzymes; molecular biophysics; molecular configurations; catalysis; cellular network; consecutive reactions; enzymes; metabolic network alignments; metabolic pathway; Biochemistry; Biological system modeling; Data mining; Diseases; Gallium; Land mobile radio cellular systems;
Conference_Titel :
Computational Advances in Bio and Medical Sciences (ICCABS), 2011 IEEE 1st International Conference on
Conference_Location :
Orlando, FL
Print_ISBN :
978-1-61284-851-8
DOI :
10.1109/ICCABS.2011.5729864